Dr. Juan J. Calvete (Valencia, Spain, 1957) is Professor of Research of the Spanish National Research Council (CSIC), Professor of PEDECIBA (Uruguay), and Head of the Venomics and Structural Proteinomics Laboratory at the Instituto de Biomedicina de Valencia (Spain). He studied Biology at the University of Valencia, and earned his Ph.D. degree in Biochemistry from Complutense University (Madrid, 1985). He completed post-doctoral training in protein chemistry and structural biology at the Banting Institute (Toronto, Canada) (1987), the Max-Planck-Institute für Biochemie (Martinsried, Germany) (1988-92), and the Institut für Reproductionsmedizin (Hannover, Germany) (1993-98) prior to assuming his current position in the Instituto de Biomedicina de Valencia in 1998. Dr. Calvete has coauthored more than 350 scientific publications, which have received 11000 citations.
His research has focused on structure-function correlations of the human integrin, IIb3, the platelet receptor for fibrinogen; proteins involved in mammalian reproduction; and snake venom disintegrins. Since his return to Spain, the Calvete´s lab has concentrated on structural and functional proteomics of snake venoms, including the development of proteomic tool (“venomics” and “antivenomics”) for exploring the evolution, composition, reactivity with antivenoms, and biotechnological applications of venoms and isolated toxins. Juan J. Calvete has served as first President of the Spanish Proteomics Society (SEProt), and is currently a member of the Congress & Communication Committe of the European Proteomics Association (EuPA), Editorial Board Member of Toxicon, Journal of Venom Research, and Toxins, and Editor-in-Chief of the Journal of Proteomics.
- Snake venomics: From the inventory of toxins to biology
- Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus
- New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India